Nucleic Acid Synthesis
Medchemexpress LLC 2'-O-Methyluridine-d3 | 2140-76-3 | 99.2% | 261.25 | 1 MG
2'-O-Methyluridine-d3 is deuterium labeled 2'-O-Methyluridine (HY-W011824). 2'-O-Methyluridine is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs. The level of 2'-O-Methyluridine in serum is decreased in patients with breast cancer. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical BrIlInt Black BN 25g
A sulfonated azo dye with antiviral activity; reduces the infectivity of EV71 in rhabdomyosarcoma cells (IC50 = 10.1 µM)
Sigma Aldrich Fine Chemicals Biosciences Thymidine >=99.0% (HPLC) | 50-89-5 | MFCD00006537 | 5G
Thymidine >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | Mol Wt: 242.23 | 50-89-5 | MFCD00006537 | 5G
Sigma Aldrich Fine Chemicals Biosciences Thymidine | 50-89-5 | MFCD00006537 | 10 g
Thymidine | Purity: ≥99% | Mol Wt: 242.23 | 50-89-5 | MFCD00006537 | 10 g
Sigma Aldrich Fine Chemicals Biosciences Thymidine >=99.0% (HPLC) | 50-89-5 | MFCD00006537 | 25G
Thymidine >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | Mol Wt: 242.23 | 50-89-5 | MFCD00006537 | 25G
Medchemexpress LLC 2'-C-methyluridine | 31448-54-1 | MFCD02682960 | ≥97.0% | 258.23 g/mol | C10H14N2O6 | 1 G
2'-C-methyluridine is a uridine nucleoside analog supplied as a white to off-white solid for laboratory research. It is used in biochemical and pharmacological studies of nucleoside analogs and as a reagent in enzymatic and antiviral assays.
- Provides a uridine analog for nucleoside research.
- High purity suitable for analytical and biochemical applications.
- Soluble in water; may require ultrasonic agitation for complete dissolution.
- Stable when stored as a powder under low-temperature conditions.
- Available in small laboratory sizes for research workflows.
Medchemexpress LLC 2′-O-Methyluridine-d3 | 2140-76-3 | 99.2% | 261.25 | 5 MG
2′-O-Methyluridine-d3 is a deuterium-labeled version of 2′-O-Methyluridine. The unlabeled compound is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA to target the gene encoding apolipoprotein B, which leads to a decrease in ApoB protein levels in HepG2 cells and prevents IFN-α production in isolated human PBMCs. Decreased levels of 2'-O-Methyluridine in serum have been observed in patients with breast cancer.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotope of hydrogen.
Apexbio Technology LLC Digoxigenin-11-dUTP 25ul (1 mM)
Digoxigenin-11-dUTP is a modified nucleotide analog designed for incorporation into DNA or cDNA by enzymatic processes substituting for natural dTTP The digoxigenin moiety attached via an 11-atom linker to the C5-position of the uridine base facilitates recognition by anti-digoxigenin antibodies labeled with horseradish peroxidase alkaline phosphatase or fluorophores Digoxigenin-11-dUTP is enzymatically incorporated using methods such as PCR amplification nick translation primer extension 3 -end labeling and reverse transcription Based on these properties Digoxigenin-11-dUTP is primarily utilized in probe-based assays sequencing and fluorescent or chromogenic in situ hybridization (ISH) applications
Medchemexpress LLC 5-methyl-2'-deoxypseudouridine | 65358-15-8 | 99.4% | 242.23 | C10H14N2O5 | 1 MG
Pseudothymidine is a C-nucleoside analog of thymidine supplied as a powdered research reagent. It serves as an alternative nucleoside substrate for molecular biology and nucleic acid studies and includes analytical data and recommended storage conditions for laboratory use.
- C-nucleoside analog of thymidine.
- Molecular formula C10H14N2O5 and molecular weight 242.23.
- High purity: 99.4%.
- Available in small milligram package sizes (1 mg, 5 mg, 10 mg).
- Powder form with storage guidance: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months) or -20°C (up to 1 month).
- For research use only; not for clinical or patient use.
